RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-22
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
TGFBR1
Pathway
NA
PubMed ID
Title
MiR-22 may Suppress Fibrogenesis by Targeting TGFBR I in Cardiac Fibroblasts
Year
2016
Function
"TGF-betaRi is a direct target for miR-22, and downregulation of TGF-betaR may have mediated the antifibrotic effect of miR-22,miR-22 acts as a novel negative regulator of angiotensin ii-induced cardiac fibrosis by suppressing the expression of TGF-betaRi."
RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-22
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; dual-luciferase reporter assay etc.
Target
TGFBR1
Pathway
NA
PubMed ID
Title
MiR-22 may Suppress Fibrogenesis by Targeting TGFBR I in Cardiac Fibroblasts
Year
2016
Function
"TGF-betaRi is a direct target for miR-22, and downregulation of TGF-betaR may have mediated the antifibrotic effect of miR-22,miR-23 acts as a novel negative regulator of angiotensin ii-induced cardiac fibrosis by suppressing the expression of TGF-betaRi."